Ownership Submission
FORM 4
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
Bloch Stephen M
   2. Issuer Name and Ticker or Trading Symbol
AMICUS THERAPEUTICS INC [FOLD] 		5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
__X__ Director _____ 10% Owner
_____ Officer (give title below) _____ Other (specify below)
(Last)
(First)
(Middle)
C/O CANAAN PARTNERS, 285 RIVERSIDE AVENUE, SUITE 250		 3. Date of Earliest Transaction (Month/Day/Year)
06/05/2007
(Street)

WESTPORT, CT 06880		 4. If Amendment, Date Original Filed(Month/Day/Year)
 6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)		 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code
(Instr. 8)		 4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)		 5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)		 6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)		 7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V Amount (A) or (D) Price
Common Stock 06/05/2007   C   1,976,967 A (1) 0 I By Canaan Equity III, L.P. (2)
Common Stock 06/05/2007   C   73,823 A (1) 0 I By Canaan Equity III Entrepreneurs, L.L.C. (3)

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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)		 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code
(Instr. 8)		 5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)		 6. Date Exercisable and Expiration Date
(Month/Day/Year)		 7. Title and Amount of Underlying Securities
(Instr. 3 and 4)		 8. Price of Derivative Security
(Instr. 5)		 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 4)		 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)		 11. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Series B Convertible Preferred Stock Warrant (right to buy) $ 6.375 06/05/2007   X     7,859 (4) 05/04/2004   (4) Series B Convertible Preferred Stock 7,859 $ 0 0 I By Canaan Equity III, L.P. (2)
Series B Convertible Preferred Stock Warrant (right to buy) $ 6.375 06/05/2007   X     253 (4) 05/04/2004   (4) Series B Convertible Preferred Stock 253 $ 0 0 I By Canaan Equity III Entrepreneurs, L.L.C. (3)
Series B Convertible Preferred Stock (5) 06/05/2007   X   7,859   06/05/2007   (5) Common Stock 7,859 $ 0 906,079 I By Canaan Equity III, L.P. (2)
Series B Convertible Preferred Stock (5) 06/05/2007   X   253   06/05/2007   (5) Common Stock 253 $ 0 33,835 I By Canaan Equity III Entrepreneurs, L.L.C. (3)
Series B Convertible Preferred Stock (1) 06/05/2007   C     7,859 06/05/2007   (1) Common Stock 449,110 $ 0 898,220 I By Canaan Equity III, L.P. (2)
Series B Convertible Preferred Stock (1) 06/05/2007   C     16,771 06/05/2007   (1) Common Stock 16,771 $ 0 33,542 I By Canaan Equity III Entrepreneurs, L.L.C. (3)
Series B Convertible Preferred Stock (1) 06/05/2007   C     449,110 05/04/2004   (1) Common Stock 449,110 $ 0 449,110 I By Canaan Equity III, L.P. (2)
Series B Convertible Preferred Stock (1) 06/05/2007   C     16,771 05/04/2004   (1) Common Stock 16,771 $ 0 16,771 I By Canaan Equity III Entrepreneurs, L.L.C. (3)
Series B Convertible Preferred Stock (1) 06/05/2007   C     449,110 03/24/2005   (1) Common Stock 449,110 $ 0 0 I By Canaan Equity III, L.P. (2)
Series B Convertible Preferred Stock (1) 06/05/2007   C     16,771 03/24/2005   (1) Common Stock 16,771 $ 0 0 I By Canaan Equity III Entrepreneurs, L.L.C. (3)
Series C Convertible Preferred Stock (1) 06/05/2007   C     437,415 08/16/2005   (1) Common Stock 437,415 $ 0 437,415 I By Canaan Equity III, L.P. (2)
Series C Convertible Preferred Stock (1) 06/05/2007   C     16,334 08/16/2005   (1) Common Stock 16,334 $ 0 16,334 I By Canaan Equity III Entrepreneurs, L.L.C. (3)
Series C Convertible Preferred Stock (1) 06/05/2007   C     437,415 04/17/2006   (1) Common Stock 437,415 $ 0 0 I By Canaan Equity III, L.P. (2)
Series C Convertible Preferred Stock (1) 06/05/2007   C     16,334 04/17/2006   (1) Common Stock 16,334 $ 0 0 I By Canaan Equity III Entrepreneurs, L.L.C. (3)
Series D Convertible Preferred Stock (1) 06/05/2007   C     96,029 09/13/2006   (1) Common Stock 98,029 $ 0 98,029 I By Canaan Equity III, L.P. (2)
Series D Convertible Preferred Stock (1) 06/05/2007   C     3,660 09/13/2006   (1) Common Stock 3,660 $ 0 3,660 I By Canaan Equity III Entrepreneurs, L.L.C. (3)
Series D Convertible Preferred Stock (1) 06/05/2007   C     96,029 09/13/2006   (1) Common Stock 98,029 $ 0 0 I By Canaan Equity III, L.P. (2)
Series D Convertible Preferred Stock (1) 06/05/2007   C     3,660 09/13/2006   (1) Common Stock 3,660 $ 0 0 I By Canaan Equity III Entrepreneurs, L.L.C. (3)
Series B Convertible Preferred Stock (1) 06/05/2007   S     5,810 (6)   (1)   (1) Series B Convertible Preferred Stock 5,810 $ 15 0 I By Canaan Equity III, L.P. (2)
Series B Convertible Preferred Stock (1) 06/05/2007   S     217 (6)   (1)   (1) Series B Convertible Preferred Stock 217 $ 15 0 I By Canaan Equity III Entrepeneurs, L.L.C. (3)

Reporting Owners

Reporting Owner Name / Address Relationships
 Director  10% Owner  Officer  Other
Bloch Stephen M
C/O CANAAN PARTNERS
285 RIVERSIDE AVENUE, SUITE 250
WESTPORT, CT 06880		   X      

Signatures

 /s/ Stephen Bloch   06/07/2007
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) Each of the Series B Convertible Preferred Stock, Series C Convertible Preferred Stock and Series D Convertible Preferred Stock automatically converted into Amicus Therapeutics, Inc. common stock on a one for one basis upon the closing of Amicus Therapeutics, Inc's initial public offering on June 5, 2007.
(2) The reporting person is a member of Canaan Equity Partners III, LLC, which is the general partner of Canaan Equity III, L.P. Voting and investment power over these shares is exercised by the managers of Canaan Equity Partners III, LLC in its role as general partner of Canaan Equity III, L.P. The reporting person disclaims beneficial ownership of these shares except to the extent of his proportionate pecuniary interest therein, and the inclusion of these shares in this report shall not be deemed an admission of beneficial ownership of the shares for purporses of Section 16 or for any other purpose.
(3) The reporting person is a member of Canaan Equity Partners III, LLC, which is the general partner of Canaan Equity III Entrepreneurs, LLC. Voting and investment power over these shares is exercised by the managers of Canaan Equity Partners III, LLC. in its role as general partner of Canaan Equity III Entrepreneurs, LLC. The reporting person disclaims beneficial ownership of these shares except to the extent of his proportionate pecuniary interest therein, and the inclusion of these shares in this report shall not be deemed an admission of beneficial ownership for purposes of Section 16 or for any other purpose.
(4) The warrants to purchase Series B Convertible Preferred Stock were automatically net exercised for shares of Series B Preferred Stock of the Issuer upon the closing of the Issuer's initial public offering on June 5, 2007.
(5) Each share is convertible and will automatically convert on a one-for-one basis into the Issuer's common stock upon the closing of the Issuer's initial public offering of common stock pursuant to an effectice registration statement filed with the U.S. Securities and Exchange Commission. These shares have no expiration date.
(6) Represents shares of Series B Convertible Preferred Stock disposed of in connection with the net exercise of warrants.

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