FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person * Brady Stephen R   2. Issuer Name and Ticker or Trading Symbol IMMUNE DESIGN CORP. [IMDZ] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) _____ Director _____ 10% Owner __X__ Officer (give title below) _____ Other (specify below) EVP, Strategy & Finance (Last) (First) (Middle) C/O IMMUNE DESIGN CORP., 1616 EASTLAKE AVE. E., SUITE 310 3. Date of Earliest Transaction (Month/Day/Year) 07/17/2018 (Street) SEATTLE, WA 98102 4. If Amendment, Date Original Filed(Month/Day/Year) 6. Individual or Joint/Group Filing(Check Applicable Line) _X_ Form filed by One Reporting Person ___ Form filed by More than One Reporting Person (City) (State) (Zip) Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned

1.Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price

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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)

1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Underlying Securities (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares
Stock Option (Rt to Buy)	$ 8.92	07/17/2018		D			27,525	(1)	06/23/2024	Common Stock	27,525	(2)	0	D
Stock Option (Rt to Buy)	$ 4.4	07/17/2018		A		18,350		(3)	07/17/2025	Common Stock	18,350	(2)	18,350	D
Stock Option (Rt to Buy)	$ 8.92	07/17/2018		D			12,230	(1)	06/23/2024	Common Stock	12,230	(4)	0	D
Stock Option (Rt to Buy)	$ 4.4	07/17/2018		A		8,154		(3)	07/17/2025	Common Stock	8,154	(4)	8,154	D
Stock Option (Rt to Buy)	$ 31	07/17/2018		D			2,838	(5)	01/07/2025	Common Stock	2,838	(6)	0	D
Stock Option (Rt to Buy)	$ 4.4	07/17/2018		A		1,419		(3)	07/17/2025	Common Stock	1,419	(6)	1,419	D
Stock Option (Rt to Buy)	$ 31	07/17/2018		D			47,162	(5)	01/07/2025	Common Stock	47,162	(7)	0	D
Stock Option (Rt to Buy)	$ 4.4	07/17/2018		A		23,581		(3)	07/17/2025	Common Stock	23,581	(7)	23,581	D
Stock Option (Rt to Buy)	$ 13	07/17/2018		D			50,000	(8)	10/30/2025	Common Stock	50,000	(9)	0	D
Stock Option (Rt to Buy)	$ 4.4	07/17/2018		A		33,334		(3)	07/17/2025	Common Stock	33,334	(9)	33,334	D
Stock Option (Rt to Buy)	$ 19.39	07/17/2018		D			5,054	(10)	01/04/2026	Common Stock	5,054	(11)	0	D
Stock Option (Rt to Buy)	$ 4.4	07/17/2018		A		2,888		(3)	07/17/2025	Common Stock	2,888	(11)	2,888	D
Stock Option (Rt to Buy)	$ 19.39	07/17/2018		D			69,946	(10)	01/04/2026	Common Stock	69,946	(12)	0	D
Stock Option (Rt to Buy)	$ 4.4	07/17/2018		A		39,970		(3)	07/17/2025	Common Stock	39,970	(12)	39,970	D
Stock Option (Rt to Buy)	$ 5.6	07/17/2018		D			14,216	(13)	01/04/2027	Common Stock	14,216	(14)	0	D
Stock Option (Rt to Buy)	$ 4.4	07/17/2018		A		9,478		(15)	07/17/2025	Common Stock	9,478	(14)	9,478	D
Stock Option (Rt to Buy)	$ 5.6	07/17/2018		D			70,784	(13)	01/04/2027	Common Stock	70,784	(16)	0	D
Stock Option (Rt to Buy)	$ 4.4	07/17/2018		A		47,190		(15)	07/17/2025	Common Stock	47,190	(16)	47,190	D

Reporting Owners

Reporting Owner Name / Address	Relationships
	Director	10% Owner	Officer	Other
Brady Stephen R C/O IMMUNE DESIGN CORP. 1616 EASTLAKE AVE. E., SUITE 310 SEATTLE, WA 98102			EVP, Strategy & Finance

Signatures

/s/ Stephen R. Brady, Attorney-In-Fact		07/19/2018
**Signature of Reporting Person		Date

Explanation of Responses:

*	If the form is filed by more than one reporting person, see Instruction 4(b)(v).
**	Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1)	The option provided for vesting of 1/4th of the shares underlying the option on June 23, 2015 and the remainder of the shares at a rate of 1/36th per month thereafter.
(2)	On July 17, 2018, the issuer canceled, pursuant to the issuer's option exchange program, an option for 27,525 shares of the issuer's common stock granted to the reporting person on June 23, 2014. In exchange, the reporting person received a replacement option, for 18,350 shares, having an exercise price of $4.40 per share.
(3)	The option vests in twenty four (24) equal consecutive monthly installments beginning on August 17, 2018.
(4)	On July 17, 2018, the issuer canceled, pursuant to the issuer's option exchange program, an option for 12,230 shares of the issuer's common stock granted to the reporting person on June 23, 2014. In exchange, the reporting person received a replacement option, for 8,154 shares, having an exercise price of $4.40 per share.
(5)	The option provided for vesting of 1/4th of the shares underlying the option on January 1, 2016 and the remainder of the shares at a rate of 1/36th per month thereafter.
(6)	On July 17, 2018, the issuer canceled, pursuant to the issuer's option exchange program, an option for 2,838 shares of the issuer's common stock granted to the reporting person on January 7, 2015. In exchange, the reporting person received a replacement option, for 1,419 shares, having an exercise price of $4.40 per share.
(7)	On July 17, 2018, the issuer canceled, pursuant to the issuer's option exchange program, an option for 47,162 shares of the issuer's common stock granted to the reporting person on January 7, 2015. In exchange, the reporting person received a replacement option, for 23,581 shares, having an exercise price of $4.40 per share.
(8)	The option provided for vesting of 37.5% of the option on each of October 30, 2016 and 2017 with the remainder of the shares underlying the option on October 30, 2018.
(9)	On July 17, 2018, the issuer canceled, pursuant to the issuer's option exchange program, an option for 50,000 shares of the issuer's common stock granted to the reporting person on October 30, 2015. In exchange, the reporting person received a replacement option, for 33,334 shares, having an exercise price of $4.40 per share.
(10)	The option provided for vesting of 1/4th of the shares underlying the option on January 4, 2017 and the remainder of the shares underlying the option at a rate of 1/36th per month thereafter.
(11)	On July 17, 2018, the issuer canceled, pursuant to the issuer's option exchange program, an option for 5,054 shares of the issuer's common stock granted to the reporting person on January 4, 2016. In exchange, the reporting person received a replacement option, for 2,888 shares, having an exercise price of $4.40 per share.
(12)	On July 17, 2018, the issuer canceled, pursuant to the issuer's option exchange program, an option for 69,946 shares of the issuer's common stock granted to the reporting person on January 4, 2016. In exchange, the reporting person received a replacement option, for 39,970 shares, having an exercise price of $4.40 per share.
(13)	The option provided for vesting of 1/4th of the shares underlying the option on January 4, 2018 and the remainder of the shares at a rate of 1/36th per month thereafter.
(14)	On July 17, 2018, the issuer canceled, pursuant to the issuer's option exchange program, an option for 14,216 shares of the issuer's common stock granted to the reporting person on January 4, 2017. In exchange, the reporting person received a replacement option, for 9,478 shares, having an exercise price of $4.40 per share.
(15)	The option vests in thirty six (36) equal consecutive monthly installments beginning on August 17, 2018.
(16)	On July 17, 2018, the issuer canceled, pursuant to the issuer's option exchange program, an option for 70,784 shares of the issuer's common stock granted to the reporting person on January 4, 2017. In exchange, the reporting person received a replacement option, for 47,190 shares, having an exercise price of $4.40 per share.

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