FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person * MOYA STEVEN O   2. Issuer Name and Ticker or Trading Symbol HUMANA INC [HUM] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) _____ Director _____ 10% Owner __X__ Officer (give title below) _____ Other (specify below) Sr. VP-Chief Marketing Officer (Last) (First) (Middle) HUMANA INC., 500 WEST MAIN STREET 3. Date of Earliest Transaction (Month/Day/Year) 09/25/2007 (Street) LOUISVILLE, KY 40202 4. If Amendment, Date Original Filed(Month/Day/Year) 6. Individual or Joint/Group Filing(Check Applicable Line) _X_ Form filed by One Reporting Person ___ Form filed by More than One Reporting Person (City) (State) (Zip) Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned

1.Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Humana Common 09/25/2007   M   5,047 A $ 21.275 34,018 D   Humana Common 09/25/2007   F   1,584 D $ 67.76 32,434 D   Humana Common 09/25/2007   M   21,667 A $ 32.7 54,101 D   Humana Common 09/25/2007   M   15,885 A $ 53.96 69,986 D   Humana Common 09/25/2007   M   10,633 A $ 21.275 80,619 D   Humana Common 09/25/2007   S   48,185 D $ 0 (10) 32,434 D   Humana Common 09/26/2007   M   2,000 A $ 21.275 34,434 D   Humana Common 09/26/2007   S   2,000 D $ 68.3 32,434 D (11)   Humana Common               1,184 I HRSP (1)

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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)

1. Title of Derivative Security (Instr. 3)

2. Conversion or Exercise Price of Derivative Security

3. Transaction Date (Month/Day/Year)

3A. Deemed Execution Date, if any (Month/Day/Year)

4. Transaction Code (Instr. 8)

5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5)

6. Date Exercisable and Expiration Date (Month/Day/Year)

7. Title and Amount of Underlying Securities (Instr. 3 and 4)

8. Price of Derivative Security (Instr. 5)

9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)

10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)

11. Nature of Indirect Beneficial Ownership (Instr. 4)

Code

V

(A)

(D)

Date Exercisable

Expiration Date

Title

Amount or Number of Shares

Options (5)

$ 32.7

09/25/2007

M

21,667

(7)

02/24/2012

Humana Common

21,667

$ 32.7

21,666

D

Options (2)

$ 12.995

(3)

03/13/2012

Humana Common

5,000

5,000

D

Options (2)

$ 9.26

(4)

03/13/2013

Humana Common

13,782

13,782

D

Options (5)

$ 21.275

09/25/2007

M

15,680

(6)

02/24/2014

Humana Common

15,680

$ 21.275

2,000

D

Options (5)

$ 21.275

09/26/2007

M

2,000

(6)

02/14/2014

Humana Common

2,000

$ 21.275

0

D

Options (5)

$ 53.96

09/25/2007

M

15,885

(8)

02/23/2013

Humana Common

15,885

$ 53.96

31,770

D

Options (5)

$ 62.1

(9)

02/22/2014

Humana Common

38,062

38,062

D

Reporting Owners

Reporting Owner Name / Address	Relationships
	Director	10% Owner	Officer	Other
MOYA STEVEN O HUMANA INC. 500 WEST MAIN STREET LOUISVILLE, KY 40202			Sr. VP-Chief Marketing Officer

Signatures

Steven O. Moya		09/26/2007
**Signature of Reporting Person		Date

Explanation of Responses:

*	If the form is filed by more than one reporting person, see Instruction 4(b)(v).
**	Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1)	Stock units held for reporting person's benefit as of August 31, 2007 under the Humana Retirement & Savings Plan including a routine disposition of shares to fund an administrative fee assessment under a Tax-Conditioned Plan, both exempt under Rule 16b-3(c).
(2)	Right to buy pursuant to the Company's 1996 Stock Incentive Plan for Employees.
(3)	Stock options granted to reporting person on 3/13/02 to vest as follows: 10,000 non-qualified stock options, one-half vesting on 3/13/03 and 3/13/04, respectively, and 5,000 incentive stock options to vest on 3/13/05.
(4)	Stock options granted to reporting person on 3/13/03 to vest as follows: 16,218 non-qualified stock options to vest in two increments - 10,000 on 3/13/04 and 6,218 on 3/13/05, and 13,782 incentive stock options to vest in two increments, 3,782 on 3/13/05 and 10,000 on 3/13/06.
(5)	Right to buy pursuant to the Company's 2003 Stock Incentive Plan.
(6)	Incentive and Non-Qualified stock options granted to reporting person on 2/24/04, NQ options vesting in three increments from 2/24/05 to 2/24/07, and ISOs vesting in two increments on 2/24/06 and 2/24/07.
(7)	Incentive and Non-Qualified stock options granted to reporting person on 2/24/05, NQ options vesting in three increments from 2/24/06 to 2/24/08, and ISO's vesting on 2/24/08.
(8)	Incentive and Non-Qualified stock options granted to reporting person on 2/23/06, NQ options vesting in three increments from 2/23/07 to 2/23/09, and ISO's vesting on 2/23/09.
(9)	Incentive and Non-Qualified stock options granted to reporting person on 2/22/07, NQ options vesting in three increments from 2/22/08 to 2/22/10, and ISO's vesting on 2/22/10.
(10)	Total of 48,185 shares sold on 9/25/2007 in the following amounts: 17,000@$68.00; 800@$68.01; 600@$68.02; 1,200@$68.03; 100@$68.04; 3,400@68.05; 2,300@$68.06; 900@$68.07; 6,700@$68.08; 600@$68.09; 200@$68.10; 5,600@$68.11; 1,800@$68.12; 200@$68.13; 300@$68.14; 1,500@$68.15; 400@$68.16; 1,385@$68.17; 500@$68.18; 100@$68.19; 200@$68.20; 500@$68.21; 100@$68.22; 700@$68.25; 700@$68.26; 100@$68.27; 100@$68.34; 100@$68.35 and 100@$68.36
(11)	Shares held in a Trust Account

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