UNITED STATES

                       SECURITIES AND EXCHANGE COMMISSION

                             WASHINGTON, D.C. 20549

                      ------------------------------------


                                    FORM 8-K

                                 CURRENT REPORT

                     PURSUANT TO SECTION 13 OR 15(D) OF THE
                         SECURITIES EXCHANGE ACT OF 1934

        Date of report (Date of earliest event reported): March 4, 2004
                                                          -------------

                               CYTOGEN CORPORATION
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               (Exact Name of Registrant as Specified in Charter)


            Delaware                    000-14879                 22-2322400
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(State or Other Jurisdiction    (Commission File Number)      (I.R.S. Employer
      of Incorporation)                                      Identification No.)

650 College Road East, CN 5308, Suite 3100, Princeton, NJ            08540
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                   (Address of Principal Executive Offices)        (Zip Code)

       Registrant's telephone number, including area code: (609) 750-8200
                                                           --------------


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          (Former Name or Former Address, if Changed Since Last Report)





ITEM 12.      RESULTS OF OPERATIONS AND FINANCIAL CONDITION.

         On March 4, 2004, Cytogen  Corporation  announced its financial results
for the quarter  and fiscal  year ended  December  31,  2003 and  provided  2004
financial guidance. The full text of the press release issued in connection with
the announcement is attached as Exhibit 99.1 to this Current Report on Form 8-K.

         The information in this Form 8-K and the exhibit  attached hereto shall
not be deemed "filed" for purposes of Section 18 of the Securities  Exchange Act
of 1934 (the  "Exchange  Act") or otherwise  subject to the  liabilities of that
section,  nor shall it be deemed  incorporated  by reference in any filing under
the Securities Act of 1933 or the Exchange Act, except as expressly set forth by
specific reference in such a filing.






                                   SIGNATURES



         Pursuant to the  requirements  of the Securities  Exchange Act of 1934,
the  Registrant  has duly  caused  this report to be signed on its behalf by the
undersigned hereunto duly authorized.

                                      CYTOGEN CORPORATION



                                      By:  /s/ Michael D. Becker
                                           -------------------------------------
                                           Michael D. Becker
                                           President and Chief Executive Officer

Dated:   March 4, 2004






                                  EXHIBIT INDEX


               Exhibit No.      Description
               -----------      -----------

                  99.1          Press release dated March 4, 2004