UNITED STATES

                       SECURITIES AND EXCHANGE COMMISSION

                             WASHINGTON, D.C. 20549

                    ----------------------------------------

                                   FORM 8-K/A

                                 CURRENT REPORT

                     PURSUANT TO SECTION 13 OR 15(d) OF THE
                         SECURITIES EXCHANGE ACT OF 1934

       Date of report (Date of earliest event reported): December 13, 2005
                                                         -----------------

                               CYTOGEN CORPORATION
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               (Exact Name of Registrant as Specified in Charter)

         Delaware                       000-14879                 22-2322400
----------------------------    ------------------------     -------------------
(State or Other Jurisdiction    (Commission File Number)      (I.R.S. Employer
      of Incorporation)                                      Identification No.)

650 College Road East, CN 5308, Suite 3100, Princeton, NJ            08540
---------------------------------------------------------       ----------------
        (Address of Principal Executive Offices)                   (Zip Code)

       Registrant's telephone number, including area code: (609) 750-8200
                                                           --------------


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          (Former Name or Former Address, if Changed Since Last Report)


     Check the  appropriate  box below if the Form 8-K  filing  is  intended  to
simultaneously  satisfy the filing obligation of the registrant under any of the
following provisions (see General Instruction A.2. below):

     |_|  Written communications  pursuant to Rule 425 under the  Securities Act
(17 CFR 230.425)

     |_|  Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17
CFR 240.14a-12)

     |_|  Pre-commencement  communications  pursuant to Rule 14d-2(b)  under the
Exchange Act (17 CFR 240.14d-2(b))

     |_|  Pre-commencement  communications  pursuant to Rule 13e-4(c)  under the
Exchange Act (17 CFR 240.13e-4(c))





ITEM 9.01    FINANCIAL STATEMENTS AND EXHIBITS

     In  connection  with the  execution  by  Cytogen  Corporation,  a  Delaware
corporation (the  "Company"),  of a Securities  Purchase  Agreement with certain
institutional investors for the sale of 3,729,556 shares of its common stock and
932,389 warrants to purchase shares of its common stock at a unit price of $3.56
per unit,  through  a  registered  direct  offering,  the  Company  executed  an
Engagement  Agreement  with Rodman & Renshaw,  LLC.  The Company is amending its
Current  Report on Form 8-K  filed on  December  14,  2005 in order to file such
Engagement Agreement.

(d) Exhibits.

        Exhibit No.       Description
        -----------       -----------

            1.1           Engagement  Agreement dated  December 13, 2005 between
                          Cytogen Corporation and Rodman & Renshaw, LLC.





                                   SIGNATURES


     Pursuant to the  requirements  of the Securities  Exchange Act of 1934, the
Registrant  has duly  caused  this  report  to be  signed  on its  behalf by the
undersigned hereunto duly authorized.

                                        CYTOGEN CORPORATION



                                        By:  /s/ Michael D. Becker
                                           -------------------------------------
                                           Michael D. Becker
                                           President and Chief Executive Officer

Dated:   December 14, 2005





                                  EXHIBIT INDEX


        Exhibit No.       Description
        -----------       -----------

            1.1           Engagement  Agreement  dated December 13, 2005 between
                          Cytogen Corporation and Rodman & Renshaw, LLC.