UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                  SCHEDULE 13G

                   Under the Securities Exchange Act of 1934
                              (Amendment No. ___)*
                                Uroplasty, Inc.
                                (Name of Issuer)

                          Common Stock, par value $.01
                         (Title of Class of Securities)

                                   917277204
                                 (CUSIP Number)

                                 June 18, 2010
            (Date of Event Which Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to which this Schedule
is filed:

[_]     Rule 13d-1(b)
[X]     Rule 13d-1(c)
[_]     Rule 13d-1(d)

*The remainder of this cover page shall be filled out for a reporting person's
initial filing on this form with respect to the subject class of securities, and
for any subsequent amendment containing information which would alter the
disclosures provided in a prior cover page.

The information required in the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the Securities Exchange Act of
1934 ("Act") or otherwise subject to the liabilities of that section of the Act
but shall be subject to all other provisions of the Act (however, see the
Notes).



PERSONS WHO ARE TO RESPOND TO THE COLLECTION OF INFORMATION CONTAINED IN THIS
FORM ARE NOT REQUIRED TO RESPOND UNLESS THE FORM DISPLAYS A CURRENTLY VALID OMB
CONTROL NUMBER.

SEC 1745 (12-02)




                         

                                13G                            Page 2 of 7 Pages


         CUSIP No. 917277204
--------- --------------------------------------------------------------------------------------------------------

          1. NAMES OF REPORTING PERSONS
          I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)

          PERCEPTIVE ADVISORS LLC

--------- --------------------------------------------------------------------------------------------------------

          2. CHECK THE APPROPRIATE BOX IF A GROUP*                                                      (a) [ ]
                                                                                                        (b) [ ]
--------- --------------------------------------------------------------------------------------------------------

          3. SEC USE ONLY



--------- --------------------------------------------------------------------------------------------------------

          4. CITIZENSHIP OR PLACE OF ORGANIZATION

          Delaware

------------------- ---- -------------------------------------------- --------------------------------------------
    NUMBER OF
      SHARES             5. SOLE VOTING POWER                                                                   0
------------------- ---- -------------------------------------------- --------------------------------------------
   BENEFICIALLY
     OWNED BY            6. SHARED VOTING POWER                                                           865,248
------------------- ---- -------------------------------------------- --------------------------------------------
       EACH
    REPORTING            7. SOLE DISPOSITIVE POWER                                                              0
------------------- ---- -------------------------------------------- --------------------------------------------
   PERSON WITH:
                         8. SHARED DISPOSTIVE POWER                                                       865,248
------------------- ---- -------------------------------------------- --------------------------------------------

          9. AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON                                 865,248
--------- ------------------------------------------------------------------------- ------------------------------

          10. CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS)        [ ]
--------- --------------------------------------------------------------------------------------------------------

          11. PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)                                              5.7%
--------- ------------------------------------------------------------------------- ------------------------------

          12. TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)                                            IA
--------- ------------------------------------------------------------------------- ------------------------------



--------------------------------------- ------------------------------------ -------------------------------------

                                                        13G                           Page 3 of 7 Pages

CUSIP No. 917277204
--------------------------------------- ------------------------------------ -------------------------------------

          13. NAMES OF REPORTING PERSONS
          I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)

          JOSEPH EDELMAN

--------- --------------------------------------------------------------------------------------------------------

          14. CHECK THE APPROPRIATE BOX IF A GROUP*                                                     (A) [ ]
                                                                                                        (B) [ ]
--------- --------------------------------------------------------------------------------------------------------

          15. SEC USE ONLY



--------- --------------------------------------------------------------------------------------------------------

          16. CITIZENSHIP OR PLACE OF ORGANIZATION

          United States of America

--------- --------------------------------------------------------------------------------------------------------
    NUMBER OF
      SHARES             17. SOLE VOTING POWER                                                                  0
------------------- ---- -------------------------------------------- --------------------------------------------
   BENEFICIALLY
     OWNED BY            18. SHARED VOTING POWER                                                          865,248
------------------- ---- -------------------------------------------- --------------------------------------------
       EACH
    REPORTING            19. SOLE DISPOSITIVE POWER                                                             0
------------------- ---- -------------------------------------------- --------------------------------------------
   PERSON WITH:
                         20. SHARED DISPOSTIVE POWER                                                      865,248
--------- ------------------------------------------------------------------------- ------------------------------

          21. AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON                                865,248
--------- --------------------------------------------------------------------------------------------------------

          22. CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS)         [ ]
--------- ------------------------------------------------------------------------- ------------------------------

          23. PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)                                              5.7%
--------- ------------------------------------------------------------------------- ------------------------------

          24. TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)                                            IN
--------- ------------------------------------------------------------------------- ------------------------------



                                                        13G                            Page 4 of 7 Pages

CUSIP No. 917277204
--------------------------------------- ------------------------------------ --------------------------------------

ITEM 1.
        (a)  Name of Issuer:           Uroplasty, Inc.

        (b)  Address of Issuer's Principal Executive Offices:  5420 Feltl Road
                                                               Minnetonka, Minnesota 55413-2820

ITEM 2.

                                          This Schedule 13G (the "Schedule") is being filed with respect to
                                          shares of Common Stock (as defined below) of Uroplasty, Inc. (the
        (a)  Name of Person Filing:       "Issuer") which are beneficially owned by Perceptive Advisors LLC and
                                          Joseph Edelman (together, the "Reporting Persons").  See Item 4 below.


                                                              Perceptive Advisors LLC
        (b)  Address  of  Principal  Business  Office  or,    499 Park Avenue, 25th Floor
             if  none, Residence:                             New York, NY 10022

        (c)  Citizenship:                 Perceptive Advisors LLC  is  a  Delaware limited liability company  and
                                          Joseph Edelman is a United States Citizen.

        (d)  Title of Class of            Common Stock, par value $.01 (the "Common Stock")
             Securities:

        (e)  CUSIP Number:                917277204



 ITEM 3.   IF THIS STATEMENT IS FILED PURSUANT TO SS.SS.240.13D-1(B) OR 240.13D-2(B) OR (C),
           CHECK WHETHER THE PERSON FILING IS A:

        (a) [ ]      Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o).
        (b) [ ]      Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c).
        (c) [ ]      Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c).
        (d) [ ]      Investment company registered under section 8  of  the Investment Company Act  of  1940  (15
                     U.S.C 80a-8).
        (e) [ ]      An investment adviser in accordance with ss.240.13d-1(b)(1)(ii)(E);
        (f) [ ]      An employee benefit plan or endowment fund in accordance with ss.240.13d-1(b)(1)(ii)(F);
        (g) [ ]      A parent holding company or control person in accordance with ss. 240.13d-1(b)(1)(ii)(G);
        (h) [ ]      A savings associations as defined in Section 3(b)  of  the Federal Deposit Insurance Act (12
                     U.S.C. 1813);
        (i) [ ]      A  church plan that  is excluded from the definition of  an investment company under section
                     3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);
        (j) [ ]      Group, in accordance with ss.240.13d-1(b)(1)(ii)(J).




                                                        13G                            Page 5 of 7 Pages

CUSIP No. 917277204
--------------------------------------- ------------------------------------ --------------------------------------

ITEM 4.  OWNERSHIP.

         Provide the following information regarding the aggregate number and percentage of the class of
securities of the issuer identified in Item 1.

                                          The Reporting Persons beneficially own 865,248 shares  of  Common Stock
                                          held  by  a  private investment fund  to  which Perceptive Advisors LLC
     (a) Amount beneficially owned:       serves  as  the investment manager. Mr. Edelman is  the managing member
                                          of Perceptive Advisors LLC.

                                          The beneficial ownership of 5.7% is based on the 15,310,040 outstanding
     (b) Percent of class:                shares of Common Stock of the Issuer, as disclosed on the Issuer's Form
                                          10-K/A filed with the SEC on June 18, 2010.

     (c)      Number of  shares  as  to  which the
              person has:

                  (i)      Sole power to vote or to direct the vote:
                                                                                        0
                  (ii)     Shared power to vote or to direct the vote:
                                                                                  865,248
                 (iii)     Sole power to dispose or to direct the disposition of:       0

                  (iv)     Shared power  to dispose or  to direct the disposition
                           of:                                                    865,248

ITEM 5. OWNERSHIP OF FIVE PERCENT OR LESS OF A CLASS

If this statement is being filed to report the fact that as of the date hereof the reporting person has ceased to
be the beneficial owner of more than five percent of the class of securities, check the following [  ].



--------------------------------------- ------------------------------------ -------------------------------------

                                                        13G                           Page 6 of 7 Pages

CUSIP No. 917277204
--------------------------------------- ------------------------------------ -------------------------------------

ITEM 6. OWNERSHIP OF MORE THAN FIVE PERCENT ON BEHALF OF ANOTHER PERSON


As referred to in Item 4, other persons have the right to receive and the power
to direct the receipt of dividends from, and the proceeds from the sale of,
certain of the shares reported herein. In that regard, Mr. Edelman is the
managing member of Perceptive Advisors LLC, the investment manager of a private
investment fund. Accordingly, the private investment fund has the right to
receive and the power to direct the receipt of, dividends and the proceeds from
the sale of the shares reported herein that are held through the private
investment fund.

ITEM 7. IDENTIFICATION AND CLASSIFICATION OF THE SUBSIDIARY WHICH ACQUIRED THE
        SECURITY BEING REPORTED ON BY THE PARENT HOLDING COMPANY OR CONTROL PERSON.

Not applicable.


ITEM 8. IDENTIFICATION AND CLASSIFICATION OF MEMBERS OF THE GROUP.

Not applicable.


ITEM 9. NOTICE OF DISSOLUTION OF GROUP.


Not applicable.

ITEM 10.  CERTIFICATION

          The following certification shall be included if the statement is
          filed pursuant to ss.240.13d-1(b):

          By signing below I certify that, to the best of my knowledge and
          belief, the securities referred to above were acquired and are
(a)       held in the ordinary course of business and were not acquired and are
          not held for the purpose of or with the effect of changing or
          influencing the control of the issuer of the securities and were not
          acquired and are not held in connection with or as a participant in
          any transaction having that purpose or effect. [X]




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                                                         13G                          Page 7 of 7 Pages

CUSIP No. 917277204
--------------------------------------- ------------------------------------ -------------------------------------

                                               SIGNATURE


         After reasonable inquiry and  to  the  best  of  my knowledge and belief, I  certify that  the
information set forth in this statement is true, complete and correct.


--------------------------------------- ------------------------------------ -------------------------------------
June 23, 2010
Date

PERCEPTIVE ADVISORS LLC

/s/ Joseph Edelman
Signature

Joseph Edelman/Managing Member
Name/Title
June 23, 2010
Date

/s/ Joseph Edelman
Signature

Joseph Edelman
Name/Title

--------------------------------------- ------------------------------------ -------------------------------------

          The original statement shall be signed by each person on whose behalf
          the statement is filed or his authorized representative. If the
          statement is signed on behalf of a person by his authorized
          representative other than an executive officer or general partner of
          the filing person, evidence of the representative's authority to sign
          on behalf of such person shall be filed with the statement, provided,
          however, that a power of attorney for this purpose which is already on
          file with the Commission may be incorporated by reference. The name
          and any title of each person who signs the statement shall be typed or
          printed beneath his signature.

          NOTE: Schedules filed in paper format shall include a signed original
          and five copies of the schedule, including all exhibits. See
          ss.240.13d-7 for other parties for whom copies are to be sent.

          ATTENTION: INTENTIONAL MISSTATEMENTS OR OMISSIONS OF FACT CONSTITUTE
          FEDERAL CRIMINAL VIOLATIONS (SEE 18 U.S.C. 1001)