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                                  UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                  SCHEDULE 13G

                    Under the Securities Exchange Act of 1934
                                (Amendment No. )*

                                 Signalife, Inc.
                                 ---------------
                                (Name of Issuer)

                    Common Stock, par value $0.001 per share
                    ----------------------------------------
                         (Title of Class of Securities)

                                    82669P10
                                    --------
                                 (CUSIP Number)

                                 August 15, 2007
                                 ---------------
            (Date of Event, which Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to which this Schedule
is filed:

|_|   Rule 13d-1(b)
|X|   Rule 13d-1(c)
|_|   Rule 13d-1(d)

*The remainder of this cover page shall be filled out for a reporting person's
initial filing on this form with respect to the subject class of securities, and
for any subsequent amendment containing information, which would alter the
disclosures provided in a prior cover page.

The information required in the remainder of this cover page shall not be deemed
to be "filed" for the purposes of Section 18 of the Securities and Exchange Act
of 1934 ("Act") or otherwise subject to the liabilities of that section of the
Act out shall be subject to all other provisions of the Act, (however, see the
Notes).



                                                                          Page 2

Cusip No. 82669P10

--------------------------------------------------------------------------------
1.    Names of Reporting Persons.
      I.R.S. Identification Nos. of above persons (entities only)

                           YA Global Investments, L.P.
                                  (13-4150836)
--------------------------------------------------------------------------------
2.    Check the Appropriate Box if a Member of a Group (See Instructions)
      (a) |_|
      (b) |_|
--------------------------------------------------------------------------------
3.    SEC Use Only


--------------------------------------------------------------------------------
4.    Citizenship or Place of Organization:

      Cayman Islands
--------------------------------------------------------------------------------

                  5.    Sole Voting Power: 4,361,325

Number of         --------------------------------------------------------------
Shares
Beneficially      6     Shared Voting Power: 0
Owned by
Each              --------------------------------------------------------------
Reporting
Person With       7.    Sole Dispositive Power: 4,361,325

                  --------------------------------------------------------------

                  8.    Shared Dispositve Power: 0

--------------------------------------------------------------------------------
9.    Aggregate Amount Beneficially Owned by Each Reporting Person:

      4,361,325
--------------------------------------------------------------------------------
10.   Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See
      Instructions) |_|

--------------------------------------------------------------------------------
11.   Percentage of Class Represented by Amount in Row (9):

      9.23%
--------------------------------------------------------------------------------
12.   Type of Reporting Person (See Instructions):

      PN
--------------------------------------------------------------------------------



                                                                          Page 3

Item 1.

      (a)   Name of Issuer: Signalife, Inc.
      (b)   Address of Issuer's Principal Executive Offices:
                  531 South Main Street, Suite 301
                  Greenville, SC 29601

Item 2.     Identity and Background.

      (a)   Name of Person Filing: YA Global Investments, L.P.
      (b)   Address of Principal Executive Office or, if none, Residence of
            Reporting Persons:
            101 Hudson Street, Suite 3700
            Jersey City, NJ 07302
      (c)   Citizenship: Cayman Islands
      (d)   Title of Class of Securities: Common Stock, par value $0.001 per
            share
      (e)   Cusip Number: 82669P10

Item 3.     If the statement is filed pursuant to ss.ss. 240.13d-1(b) or
            240.13d-2(b) or (c), check whether the person filing is:

      (a)   |_|   Broker or dealer registered under section 15 of the Act (15
                  U.S.C. 78o);
      (b)   |_|   Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);
      (c)   |_|   Insurance company as defined in section 3(a)(19) of the Act
                  (15 U.S.C. 78c);
      (d)   |_|   Investment company registered under section 8 of the
                  Investment Company Act of 1940 (15 of the Act (15 U.S.C. 78o);
      (e)   |_|   An investment adviser in accordance with
                  ss.240.13d-1(b)(1)(ii)(E);
      (f)   |_|   An employee benefit plan or endowment fund in accordance with
                  ss.240.13d-1(b)(1)(ii)(F);
      (g)   |_|   A parent holding company or control person in accordance with
                  ss.240.13d-1(b)(1)(ii)(G);
      (h)   |_|   A savings associations as defined in Section 3(b) of the
                  Federal Deposit Insurance Act (12 U.S.C. 1813);
      (i)   |_|   A church plan that is excluded from the definition of an
                  investment company under section 3(c)(14) of the Investment
                  Company Act of 1940 (15 U.S.C. 80a-3); or
      (j)   |_|   Group, in accordance with 240.13d(b)(1)(ii)(J).

Item 4.     Ownership

Provide the following information regarding the aggregate number and percentage
of the class of securities of the issuer identified in Item 1.

      (a)   Amount beneficially owned: 4,361,325

      (b)   Percentage of Class: 9.23%

      (c)   Number of shares as to which the person has:

            (i)   Sole Power to vote or to direct the vote: 4,361,325

            (ii)  Shared power to vote or to direct the vote: 0

            (iii) Sole power to dispose or to direct the disposition: 4,361,325

            (iv)  Shared power to dispose or to direct the disposition: 0



                                                                          Page 4

Item 5.     Ownership of Five Percent or Less of a Class:

If this statement is being filed to report the fact that as of the date hereof
the reporting person has ceased to be the beneficial owner of more than five
percent of the class of securities, check the following |_|.

Item 6.     Ownership of more than five percent on Behalf of Another Person.

                                 Not Applicable

Item 7.     Identification and Classification of the Subsidiary Which Acquired
            the Security Being Reported on By the Parent Holding Company or
            Control Person.

                                 Not Applicable

Item 8.     Identification and Classification of Member Group

                                 Not Applicable

Item 9.     Notice of Dissolution of Group

                                 Not Applicable

Item 10.   Certification

By signing below, I certify that, to the best of my knowledge and belief, the
securities referred to above were not acquired and are not held for the purpose
of or with the effect of changing or influencing the control of the issuer of
the securities and were not acquired and are not held in connection with or as
participant in any transaction having that purpose or effect.



                                                                          Page 5

                                    SIGNATURE

After reasonable inquiry and to the best of my knowledge and belief, I certify
that the information set forth in this statement in true, complete and correct.


Dated: August 16, 2007                  REPORTING PERSON:

                                        Yorkville Advisors, LLC
                                        as Investments Manager
                                        To: YA Global Investments, L.P

                                        By: /s/ Steven S. Goldstein
                                            ------------------------------------
                                        Name: Steven S. Goldstein, Esq.
                                        Its: Chief Compliance Officer