Disseminated on behalf of Onco-Innovations Ltd. (CBOE CA: ONCO) (OTCQB: ONNVF) and may include paid advertising.
- Onco-Innovations is advancing a new class of DNA Damage Response (“DDR”) therapies through the development of Polynucleotide Kinase Phosphatase (“PNKP”) inhibitors designed to disrupt cancer cells’ ability to repair DNA damage.
- The company recently achieved a key manufacturing milestone with the successful advancement toward kilogram-scale production of the active pharmaceutical ingredient in its lead drug candidate, ONC010.
- A newly signed Letter of Intent with Nanosoft Polymers is expected to support polymer development, drug delivery optimization and formulation work for the ONC010 program.
Cancers frequently exhibit defective repair of damaged DNA, leading to the accumulation of mutations that can give rise to unchecked growth, evasion of the immune system, and the capacity to spread. Conventional DNA damaging therapies, like radiation treatment or some chemotherapies, can overwhelm a cancer’s limited repair capacity resulting in cancer cell death. However, some cancers retain sufficient DNA repair capacity to resist these treatments at doses patients can tolerate.
Onco-Innovations (CBOE CA: ONCO) (OTCQB: ONNVF) is positioning itself within this rapidly evolving area of oncology through the development of Polynucleotide Kinase Phosphatase (“PNKP”) inhibitors. PNKP plays a critical role in repairing damaged DNA, and the company’s…
NOTE TO INVESTORS: The latest news and updates relating to ONNVF are available in the company’s newsroom at ibn.fm/ONNVF
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