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Evolv Launches With First-Ever Oral Biomimetic Supplement to Deliver GLP-1 Naturally

Pioneering biomimetics company introduces the first ingestible, natural GLP-1 peptide designed for effective and accessible weight management

Evolv, a biomimetics company redefining longevity and well-being through nature-powered science, publicly launched today with the debut of its inaugural product: Evolv GLP-1. The first-of-its-kind, oral GLP-1 supplement was created using a proprietary yeast strain engineered to produce a new molecule that delivers the full power of GLP-1 naturally. This breakthrough, non-habituating supplement is designed to help people take control of their appetite, metabolism, and long-term wellness—without side effects or barriers to access.

This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20250903111371/en/

Evolv GLP-1’s formula naturally activates the body's GLP-1 production to support weight loss and healthy blood glucose levels (Photo credit: Paris Tilley)

Evolv GLP-1’s formula naturally activates the body's GLP-1 production to support weight loss and healthy blood glucose levels (Photo credit: Paris Tilley)

“GLP-1 is a natural hormone found in your body that helps signal fullness and satiety. We've created a product that mimics the effects of GLP-1, helping you feel fuller longer, and allowing you to approach your nutrition and food choices with a sense of calm intention, rather than impulsive craving,” said Becca McCarthy, MBA, co-founder, president, and chief operating officer of Evolv. “This isn’t just another supplement. We’re building a new category at the intersection of biology and accessibility to reimagine how people take control of their metabolism, appetite, and longevity with solutions that deliver real results and work with the body—not against it.”

Biomimetics: The Next Frontier in Wellness

With the introduction of Evolv GLP-1, the company unveils a new category of health technology: biomimetics. Biomimetics are biologically engineered molecules designed to mimic and enhance the natural functions of the human body. Unlike synthetic compounds, these molecules recreate the body’s natural processes using food-safe organisms from nature and are free of stimulants and habit-forming ingredients, and unwanted side effects.

Evolv’s biomimetics are possible due to a world-class team of scientists and bioengineers with deep expertise in synthetic biology, molecular design, and therapeutic innovation leveraging AI-driven molecular modeling. Led by Co-Founder and Chief Technology Officer Kwang-Chul Kwon, PhD, and Cory Henderson, PhD, the science team also includes Christina Bergey, PhD, assistant professor of genetics at Rutgers University, and Justin Smith, PhD, founder of Recombia Bioscience.

The Current GLP-1 Market Was Built for Disease. Evolv Was Built for You.

More than 73% of adults in the U.S. are overweight, and over 40 million have turned to synthetic GLP-1 drugs for answers. In recent years, GLP-1 prescriptions have increased by over 400% for those suffering from chronic disease and also those eager to explore the promise they offer for metabolic health. Yet half of adults have trouble affording these solutions, and millions suffer adverse side effects due to the drugs’ synthetic simulation of GLP-1 at extreme doses.

As the public metabolic health crisis rises and demand for solutions grows, Evolv is changing the status quo with a radically different approach. Unlike traditional supplements, Evolv GLP-1 provides lasting appetite control, reduced food noise, and enhanced metabolic function to support steady energy and satiety all day long. By balancing hunger signals, improving digestion, and optimizing nutrient absorption, Evolv GLP-1 is the solution for healthy individuals seeking an effective weight management solution, not designed for the treatment of disease.

“We've created a new version of our body's own GLP-1 that can withstand digestion, be absorbed from a pill, and promote the body’s natural signaling pathways responsible for appetite and metabolic function with no eligibility barriers,” said Cory Henderson, PhD, co-founder and chief executive officer at Evolv. “It’s a molecular breakthrough that can transform how we support metabolic health and opens the door to a whole new era of efficacious biologics.”

A Next-Gen Formula Rooted in Nature

Evolv GLP-1 contains a single active ingredient, EV1 Peptide, composed solely of canonical amino acids. This application leverages cutting-edge genetic engineering to modify a proprietary yeast powder, derived from yeast hydrolysate, which is clinically demonstrated to activate the body’s natural GLP-1 production. Developed by leading bioengineers and scientists, Evolv GLP-1 works in alignment with normal digestive processes and is manufactured using food-safe ingredients.

Unlike many supplements that are not bioavailable–low absorption–and use artificial fillers, Evolv GLP-1 is natural, vegan, and allergen-free. The formula is designed to include only purposeful, high-quality ingredients that ensure optimal effectiveness, bioavailability, and seamless integration into any dietary lifestyle.

Evolv GLP-1 is manufactured in the USA in a cGMP-compliant facility and formulated under all applicable FDA guidelines. Each batch undergoes third-party testing to ensure purity, potency, and safety. To date, three studies have been completed on the Evolv GLP-1 formulation, with a fourth clinical trial currently underway. These studies have measured both safety and efficacy across key biomarkers related to appetite regulation, metabolic function, and nutrient absorption.

Evolving the Human Experience

Evolv GLP-1 is the first of many biomimetic supplements in the company’s pipeline that will provide natural solutions for key health needs. Evolv plans to apply its proprietary technology to areas such as hair health and restoration, among other focuses.

Evolv GLP-1 is available exclusively on evolvlife.com. Follow the brand on Instagram to join the movement and unlock the future of your wellness on your terms.

About Evolv

Evolv is a molecular health company pioneering biomimetics and the next generation of nature-powered wellness solutions. Built at the intersection of public health and consumer innovation, Evolv formulates effective, natural, and accessible solutions that activate the body’s natural pathways for metabolic, hormonal, and long-term wellbeing. The company’s flagship product, Evolv GLP-1, is the first oral supplement to deliver the full power of GLP-1 naturally. With a focus on efficacy, accessibility, and longevity, Evolv is shaping the future of wellness innovation. Learn more at evolvlife.com.

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